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  1. Marcia Joffe-Bouska, The Book of Bad Things-Volume 1, Women – No Passage | MONA
  2. Out of the Shadows
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Diagnosis was based on symptomatology, cystometry, and micturating cystograms. A total of 2 patients had been in chronic retention with residual volumes more than ml. All were managed with an injection of botulinum toxin, units in 2 ml of saline injected with a flexible cystoscopic needle. The site of the injection was deep submucosally, 0. All the procedures were done as day care procedures under local anaesthesia.

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After the procedure, no catheter was placed. Patients were followed up for changes in IPSS scores and post void residual urine measurements.

Marcia Joffe-Bouska, The Book of Bad Things-Volume 1, Women – No Passage | MONA

In all cases, multiple injections were used. Results: The follow-up period ranged from weeks.

The IPSS reduced by an average of 12 points. Improvements commenced 4.

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Discussion: There is a gradual improvement in symptoms over time and the maximal effect occurred at days. The duration of improvement was approximately All patients were satisfied by the degree of improvement felt. Conclusions: Botulinum toxin proved successful in improving the voiding characteristics. It possibly acts at the zone of hypertonicity at the bladder neck or midurethra. The only disadvantage is the high cost of the drug. Users online: Current Issue. Ahead of print. Editorial Board.

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How to cite this article: Pradhan AA. Botulinum toxin: An emerging therapy in female bladder outlet obstruction. Indian J Urol ; Materials and Methods. Patel R, Nitti V.

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Bladder outlet obstruction in women: prevalence, recognition, and management. Curr Urol Rep ; No abstract is available for this article. Citing Literature.

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